{"id":753,"date":"2017-08-19T02:31:02","date_gmt":"2017-08-19T02:31:02","guid":{"rendered":"http:\/\/emultrasound.sdsc.edu\/?p=753"},"modified":"2020-07-22T00:09:38","modified_gmt":"2020-07-22T00:09:38","slug":"case-4-to-bolus-or-not-to-bolus","status":"publish","type":"post","link":"https:\/\/emultrasound.ucsd.edu\/index.php\/2017\/08\/19\/case-4-to-bolus-or-not-to-bolus\/","title":{"rendered":"Case # 4: To Bolus or Not to Bolus?"},"content":{"rendered":"<div class=\"mp-row-fluid motopress-row mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-clmn mp-span12  mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-text-obj\">\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\">A 67 year old male with a PMHx of DM presents with a chief complaint of cough and generalized weakness.<\/p>\n<p style=\"text-align: center;\">Vitals: T 102.4 HR\u00a0127\u00a0BP\u00a077\/58\u00a0\u00a0RR\u00a024\u00a0O2\u00a088% on RA<\/p>\n<p style=\"text-align: center;\">You place the patient on O2 via nasal cannula and activate the sepsis protocol. He is empirically treated with broad spectrum antibiotics and IVFs are started. The chest x-ray shows multifocal pneumonia and you call hospital medicine to admit the patient.\u00a0 \u201cWhat\u2019s the blood pressure now,\u201d the hospitalist asks. You glance at the monitor and murmur back, \u201c92\/63, but he looks pretty good.\u201d The hospitalist asks you to insert a central line, start vasopressors, and contact the ICU. Instead, you wheel the ultrasound machine into his room, and ultrasound his IVC. Does this patient require a central line and vasopressors?<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mp-row-fluid motopress-row mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-clmn mp-span12  mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-grid-gallery-obj motopress-grid-gallery-obj-basic\"><div class=\"mp-row-fluid\"><div class=\"mp-span6\"><a href=\"https:\/\/i0.wp.com\/emultrasound.ucsd.edu\/wp-content\/uploads\/2017\/08\/Screen-Shot-2017-08-18-at-6.43.58-PM-1.png?fit=1301%2C900&ssl=1\" data-action=\"motopressGalleryLightbox\" target=\"_self\" title=\"Screen Shot 2017-08-18 at 6.43.58 PM\"><img decoding=\"async\" src=\"https:\/\/i0.wp.com\/emultrasound.ucsd.edu\/wp-content\/uploads\/2017\/08\/Screen-Shot-2017-08-18-at-6.43.58-PM-1.png?fit=1301%2C900&ssl=1\" title=\"Screen Shot 2017-08-18 at 6.43.58 PM\" alt=\"Long Axis View of IVC\" \/><\/a><p class=\"motopress-image-caption\">Long Axis View of IVC<\/p><\/div><div class=\"mp-span6\"><a href=\"https:\/\/i0.wp.com\/emultrasound.ucsd.edu\/wp-content\/uploads\/2017\/08\/Screen-Shot-2017-08-18-at-6.44.06-PM-1.png?fit=1302%2C901&ssl=1\" data-action=\"motopressGalleryLightbox\" target=\"_self\" title=\"Screen Shot 2017-08-18 at 6.44.06 PM\"><img decoding=\"async\" src=\"https:\/\/i0.wp.com\/emultrasound.ucsd.edu\/wp-content\/uploads\/2017\/08\/Screen-Shot-2017-08-18-at-6.44.06-PM-1.png?fit=1302%2C901&ssl=1\" title=\"Screen Shot 2017-08-18 at 6.44.06 PM\" alt=\"M-mode: IVC collapse with respiratory variation\" \/><\/a><p class=\"motopress-image-caption\">M-mode: IVC collapse with respiratory variation<\/p><\/div><\/div><\/div>\n<\/div>\n<\/div>\n<div class=\"mp-row-fluid motopress-row mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-clmn mp-span12  mpce-prvt-517-59604dcdd5a2a mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-accordion-obj mpce-prvt-517-5960471ed59dc motopress-accordion motopress-accordion-dark\" data-atts=\"{&quot;active&quot;:&quot;false&quot;,&quot;collapsible&quot;:true,&quot;header&quot;:&quot;&gt; div &gt; h3&quot;,&quot;heightStyle&quot;:&quot;content&quot;}\">\n<div class=\"motopress-accordion-item\"><h3>Answer and Learning Point<\/h3><div>\n<p style=\"text-align: center;\"><strong>Answer<\/strong><\/p>\n<p style=\"text-align: center;\"><span class=\"s1\">No, the patient\u2019s IVC is small and collapsing almost 75% with normal respiratory variation. This predicts a fluid-responsive state. The patient was given another liter of lactated ringers, his blood pressure improved to 108\/69, and his lactate cleared. You start maintenance IV fluids, call the hospitalist back, and the patient is admitted upstairs and does well.<\/span><\/p>\n<p style=\"text-align: center;\"><strong>Learning Points<\/strong><\/p>\n<ul>\n<li style=\"text-align: center;\">\n<ul>\n<li style=\"text-align: left;\">Fluid responsiveness is a controversial topic that continues to plague emergency medicine physicians and intensivists alike<\/li>\n<li style=\"text-align: left;\">In patients whom a fluid bolus is being considered, ultrasound can be a useful tool to assess for cardiac function, lung fluid status (interstitial edema) and whether a patient will improve their cardiac output in response to this fluid challenge<\/li>\n<li style=\"text-align: left;\">A recent study showed that the cIVC (inferior vena cava collapsibility) can be used as a predictor of who will be a fluid responder [1]\n<ul>\n<li style=\"text-align: left;\"><strong>cIVC<\/strong> = (IVC expiratory diameter - IVC inspiratory diameter)\/IVC expiratory diameter<\/li>\n<li style=\"text-align: left;\">Patients with a <strong>cIVC &gt; 25% are likely to be fluid responders<\/strong> (LR + 4.56)<\/li>\n<li style=\"text-align: left;\">Patients with a <strong>cIVC &lt; 25% are unlikely to be fluid responders<\/strong> (LR - 0.16)<\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align: left;\">The IVC should be examined in the subxiphoid region with the probe in a sagittal plane, and can be found by first identifying the right atrium and following this caudally\n<ul>\n<li style=\"text-align: left;\">A back-up approach involves using the liver as an acoustic window , placing the probe in the mid axillary line in a coronal plane, \u00a0and fanning anteriorly and posteriorly until the IVC is visualized<\/li>\n<li style=\"text-align: left;\">The IVC should be measured 3 cm caudal to the junction of the right atrium and IVC [2]<\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align: left;\">M-mode can be used to evaluate the cIVC and has the advantage of measuring the exact same spot along the IVC over an extended period of time<\/li>\n<li style=\"text-align: left;\">As with all adjuncts to clinical decision making, fluid responsiveness should not be determined solely on a single ultrasound measurement such as cIVC but should be taken into context with the rest of the clinical picture<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<div class=\"mceTemp\"><\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mp-row-fluid motopress-row mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-clmn mp-span12  mpce-dsbl-margin-left mpce-dsbl-margin-right\">\n<div class=\"motopress-accordion-obj mpce-prvt-707-5985662dc5e2b motopress-accordion motopress-accordion-dark\" data-atts=\"{&quot;active&quot;:&quot;false&quot;,&quot;collapsible&quot;:true,&quot;header&quot;:&quot;&gt; div &gt; h3&quot;,&quot;heightStyle&quot;:&quot;content&quot;}\">\n<div class=\"motopress-accordion-item\"><h3>Author<\/h3><div>\n<p>This post was written by Amir Aminlari, MD, Ultrasound Fellowship Director at UCSD.<\/p>\n<\/div><\/div>\n<div class=\"motopress-accordion-item\"><h3>References<\/h3><div>\n<p style=\"text-align: center;\">Corl KA, e. (2017). Inferior vena cava collapsibility detects fluid responsiveness among spontaneously breathing critically-ill patients. - PubMed - NCBI . Ncbi.nlm.nih.gov. Retrieved 19 August 2017, from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28525778<\/p>\n<p style=\"text-align: center;\">Nagdev AD, e. (2017). Emergency department bedside ultrasonographic measurement of the caval index for noninvasive determination of low central venous pressure. - PubMed - NCBI . Ncbi.nlm.nih.gov. Retrieved 19 August 2017, from https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19556029<\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"&nbsp; &nbsp; A 67 year old male with a PMHx of DM presents with a chief complaint of cough and generalized weakness. Vitals: T 102.4 HR\u00a0127\u00a0BP\u00a077\/58\u00a0\u00a0RR\u00a024\u00a0O2\u00a088% on RA You place the patient on O2 via nasal cannula and activate the sepsis protocol. He is empirically treated with broad spectrum antibiotics and IVFs are started. The &hellip; <p class=\"link-more\"><a href=\"https:\/\/emultrasound.ucsd.edu\/index.php\/2017\/08\/19\/case-4-to-bolus-or-not-to-bolus\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> \"Case # 4: To Bolus or Not to Bolus?\"<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_eb_attr":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[4],"tags":[7,20,22,21],"class_list":["post-753","post","type-post","status-publish","format-standard","hentry","category-clinical-cases","tag-echocardiography","tag-hemodynamics","tag-ivc","tag-volume-assessment"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Case # 4: To Bolus or Not to Bolus? - UCSD Ultrasound<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/emultrasound.ucsd.edu\/index.php\/2017\/08\/19\/case-4-to-bolus-or-not-to-bolus\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Case # 4: To Bolus or Not to Bolus? - UCSD Ultrasound\" \/>\n<meta property=\"og:description\" content=\"&nbsp; &nbsp; A 67 year old male with a PMHx of DM presents with a chief complaint of cough and generalized weakness. Vitals: T 102.4 HR\u00a0127\u00a0BP\u00a077\/58\u00a0\u00a0RR\u00a024\u00a0O2\u00a088% on RA You place the patient on O2 via nasal cannula and activate the sepsis protocol. He is empirically treated with broad spectrum antibiotics and IVFs are started. 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